By A. R. Forsyth

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Additional info for CALCULUS OF VARIATIONS

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In one case the components of conventional systems can be scaled down to produce portable equipment—for example, for field use. 1 mm, with different sample injection methods, and also with miniaturized detectors. This is accompanied by online sample processing operations, which can be different from those in conventional flow analysis instrumentation. , Ruzicka and Hansen, 1984). Progress in micromechanics and materials science produced a significant decrease of dimensions of such devices over the last two decades to allow authentic microfluidics for a wide potential of applications, for example, in environmental and clinical analysis (Gardeniers and Van Den Berg, 2004).

E. Lenehan, and S. W. Lewis. 1999. Sequential injection analysis: An alternative approach to process analytical chemistry. Trends Anal. Chem. 18:346–353. Beauchemin, D. and A. A. Specht. 1997. On-line isotope dilution analysis with ICPMS using reverse flow injection. Anal. Chem. 69:3183–3187. , H. G. Infante, and F. C. Adams. 2002. Inductively coupled plasma mass spectrometry for trace analysis using flow injection on-line preconcentration and time-of-flight mass analyzer. Trends Anal. Chem. 21:332–340.

12b. It is made from a rectangular acrylic block with crossing cylindrical channels drilled out perpendicularly. The main channel serves as the analytical flow path and is filled with the carrier solution, whereas four perpendicular channels are made for introducing segments of reagents’ solutions and sample. , 2013). 4 CONCLUSIONS: CURRENT TRENDS AND PERSPECTIVES More than half a century of development of various concepts of laboratory flow analysis earned it solid place among instrumental methods of modern chemical analysis.

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