By Niels Foged Vaduz
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Extra info for Diatoms in Oland, Sweden
In m u s c l e at 3% as a c t i v e and every and a_. 0 μΜ initiates also and dependent completely concentration in largely glucose-6P, and substrate absence However required Phosphorylase Phosphorylase phorylated are the for P h o s p h o r y l a s e J D ( 2 ) . effect how enzymes article by p h o s p h o r y l a t i o n when while activity. Enzymes them saturating inactive, no this achieving as a d e p h o s p h o r y l a t e d completely by limiting of towards interconverted In antagonised is to d i s c o v e r rate review).
The p r o t e i n is p h o s p h o r y l a t e d at one site and the amino acid s e q u e n c e in this region was shown to be: i l e - a r g - a r g - a r g - a r g - p r o - t h r ( Ρ ) - p r o - a l a - t h r - ( 3 7 ) . The p h o s p h o r y l a t e d d e c a p e p t i d e is o v e r 1 0 0 0 - t i m e s less i n h i b i t o r y than i n h i b i t o r - 1 , so that the i n h i b i t o r y p o w e r does not simply r e s i d e in the s e q u e n c e of a few 37 P. amino acids at the site of Cohen phosphorylation.
B i o l . Chem. 2 4 0 , 9 8 2 - 9 8 5 (1 965) . J. , E u r . J. B i o c h e m . 5 1 , 93-1 04 (1 9 7 5 ) . W. , FEBS Lett. 6 7 , 17-22 ( 1 9 7 6 ) . F. , P r o c . Nat. A c a d . S e i . 6 4 , 1 3 4 9 - 1 3 5 5 ( 1 9 6 9 ) . G. , Adv. C y c . N u c . R e s . 8, in press ( 1 9 7 7 ) . B. , in M e t a b o l i c I η t e r c o n v e r s i o n s of Enzymes 1975, p p . 1 4 2 - 1 4 9 , ed. , S p r i n g e r - V e r l a g , Heidelberg. (1976). , M a g n i , G. , in M e t a b o l i c I n t e r c o n v e r s i o n s of E n z y m e s 1 9 7 3 , p p .