Drug Discovery: A History by Walter Sneader

By Walter Sneader

Written by way of a number one authority with an outstanding popularity and skill for writing a superb narrative, Drug Discovery: A History is a miles cry from easily a listing of chemical buildings.

This vigorous new textual content considers the origins, improvement and heritage of medications that generate excessive media curiosity and feature a tremendous social and financial effect on society.

Set inside of a large old, social and cultural context, it offers elevated insurance of pre-twentieth century medicines, the large advances made within the 20th century and the newest advancements in drug examine.

Hallmark features:

  • Up-to-the-minute info in drug research
  • Vignettes of unique and strange info, and anecdotes
  • Discusses drug prototypes from all sources
  • More accomplished than different volumes on historical past of drug discovery

From the reviews:

"...an first-class bibliographic source for these drawn to the historical past papers that function the basis for discovery of particular drug entities." magazine OF scientific CHEMISTRY, June 2006

"...a very complete review of drug improvement. it may be at the shelf on any aspiring pharmacist, medicinal chemist, or individual attracted to the heritage of healing agents." magazine OF CHEMICAL schooling, February 2006

"...a very readable and heavily researched book..." CHEMISTRY & undefined, October 2005

Content:
Chapter 1 creation (pages 1–7):
Chapter 2 The Prehistoric interval (pages 6–11):
Chapter three Pre?Hellenic Civilisations (pages 12–17):
Chapter four Greece and Rome (pages 18–23):
Chapter five The Arab international (pages 24–31):
Chapter 6 Herbals (pages 32–40):
Chapter 7 Chemical drugs (pages 41–73):
Chapter eight Systematic medication (pages 74–87):
Chapter nine Alkaloids (pages 88–105):
Chapter 10 Non?Alkaloidal Plant items (pages 106–114):
Chapter eleven Plant Product Analogues and Compounds Derived from Them (pages 115–150):
Chapter 12 The Origins of Hormone remedy (pages 151–154):
Chapter thirteen Neurohormones (pages 155–163):
Chapter 14 Peptide Hormones (pages 164–172):
Chapter 15 intercourse Hormones (pages 173–178):
Chapter sixteen Adrenal Cortex Hormones (pages 179–184):
Chapter 17 Prostaglandins (pages 185–187):
Chapter 18 Hormone Analogues (pages 188–225):
Chapter 19 supplements (pages 226–247):
Chapter 20 Antimetabolites (pages 248–268):
Chapter 21 Blood and organic items (pages 269–286):
Chapter 22 Antibiotics (pages 287–318):
Chapter 23 Antibiotic Analogues (pages 319–340):
Chapter 24 Pharmacodynamic brokers from Micro?Organisms (pages 341–348):
Chapter 25 Analogues of Pharmacodynamic brokers from Fungi (pages 349–354):
Chapter 26 the 1st artificial medications and Their Analogues (pages 355–374):
Chapter 27 medicinal drugs Originating from the Screening of Dyes (pages 375–402):
Chapter 28 medicinal drugs Originating from the Screening of natural chemical compounds (pages 403–431):
Chapter 29 medicinal drugs came upon via Serendipitous Observations related to people (pages 432–437):
Chapter 30 medicinal drugs found via Serendipity within the Laboratory (pages 438–445):
Chapter 31 Concluding comments (pages 446–447):

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Sample text

Many editions were published, the later ones featuring large woodcuts that greatly assisted identification of the plants. HERBS FROM THE NEW WORLD The early herbals were written at the same time as the voyages of discovery were opening up new trades routes. Fernandez de Oviedo y Valdes, a Viceroy of Mexico, sent the first account of medicinal plants from the Americas to King Charles V of Spain. This was published in Toledo in 1525 as Sumario dela Natural y General Istoria delas Indias, but it had little impact compared to the contribution from Nicolas Monardes (1493–1588), a physician who practised in Seville, a port with a monopoly in trade with the Americas.

R. Wright, Empedocles: The Extant Fragments. New Haven: Yale University Press; 1981. P. Kingsley, Ancient Philosophy, Mystery and Magic: Empedocles and Pythagorean Tradition. Oxford: Oxford University Press; 1995. J. B. DeBevoise. Baltimore: Johns Hopkins University Press; 1999. V. Nutton, Humoralism, in Companion Encyclopedia of the History of Medicine, Vol. F. Bynum, R. Porter. New York: Routledge; 1993, pp. 281–91. F. Hort. Cambridge: Loeb Classical Library; 1916. Theophrastus, De Causis Plantarum, 3 vols, translated by B.

The fact that it was distributed by the Jesuits led to an element of religious bigotry adding to the confusion, and it was only the efforts of an English quack, Robert Talbor, that finally ensured Jesuits’ bark a role in medicine. Talbor was an apprentice to an apothecary in Cambridge, where the Professor of Physic, Robert Brady, had begun to prescribe the bark in 1658 during a serious outbreak of malaria. Talbor moved to London, where he treated many cases of malaria with a secret remedy. In 1672, he published a small book called A Rational Account of the Cause and Cure of Agues.

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