fMRI: From Nuclear Spins to Brain Functions by Kamil Uludag, Kamil Ugurbil, Lawrence Berliner

By Kamil Uludag, Kamil Ugurbil, Lawrence Berliner

This quantity explores the innovative fMRI box from easy rules to cutting-edge examine. It covers a extensive spectrum of issues, together with the background of fMRI's improvement utilizing endogenous MR blood distinction, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visible method, auditory cortex, and sensorimotor process; genetic imaging utilizing fMRI, multimodal neuroimaging, mind bioenergetics and serve as and molecular-level fMRI. complete and intuitively based, this publication engages the reader with a first-person account of the improvement and background of the fMRI box by way of the authors. the following sections study the physiological foundation of fMRI, the fundamental ideas of fMRI and its purposes and the newest advances of the expertise, finishing with a dialogue of fMRI’s destiny. fMRI: From Nuclear Spins to mind functionality, co-edited through best and popular fMRI researchers Kamil Ugurbil, Kamil Uludag and Lawrence Berliner, is a perfect source for clinicians and researchers within the fields of neuroscience, psychology and MRI physics.

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fMRI: From Nuclear Spins to Brain Functions

This quantity explores the innovative fMRI box from simple ideas to state of the art examine. It covers a large spectrum of themes, together with the historical past of fMRI's improvement utilizing endogenous MR blood distinction, neurovascular coupling, pulse sequences for fMRI, quantitative fMRI; fMRI of the visible method, auditory cortex, and sensorimotor method; genetic imaging utilizing fMRI, multimodal neuroimaging, mind bioenergetics and serve as and molecular-level fMRI.

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O. Vogt-Institute for Brain Research, Heinrich Heine University, Düsseldorf, Germany © Springer New York 2015 K. Uludağ et al. 1007/978-1-4899-7591-1_4 27 28 K. Zilles and K. Amunts • The regionally and laminar-specific expression of transmitter receptors is a powerful tool to delineate unimodal sensory areas from motor regions as well as multimodal association areas. The multi-receptor mapping enables the parcellation of the cortex to a previously not available detail and provides information about the molecular basis of perception, motor control and various neuronal mechanisms.

2005; Barnikol et al. 2006; Papadelis et al. 2011). This is presently the only way to establish architectonical–functional correlations in the living, non-lesioned human brain at the most precise and functionally relevant anatomical scale. Cytoarchitecture and Functions The cytoarchitectonic parcellation of the cerebral cortex relies on tissue properties reliably detectable by microscopic observations only. Cytoarchitecture reveals both structural and functional principles of cortical organization.

To demonstrate the general usefulness of the BOLD and flow-weighted type of techniques in different cortical regions, I obtained later motor cortex activation with finger tapping. 5 T. The EPI MRI system at MGH, installed by Advanced 22 K. K. Kwong NMR Systems (ANMR), was a perfect marriage for fMRI research under the expert guidance of Dr. Mark Cohen and Dr. Robert Weisskoff. Single-shot EPI also laid bare any contribution of motion artifacts which became in principle manageable through judicious choice of motion correction algorithms.

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