Human Health: The Contribution of Microorganisms by G. W. Tannock (auth.), Dr Stewart A. W. Gibson (eds.)

By G. W. Tannock (auth.), Dr Stewart A. W. Gibson (eds.)

Human health and wellbeing: The Contribution of Microorganisms is the 1st significant paintings to be aware of probiotics in people. It provides either new and proven facts at the origins and value of commensal floras, the heritage and features of probiotics, using probiotics in scientific events, and preclinical and volunteer reports. It additionally covers advertisement concerns corresponding to the problems fascinated about the big scale construction and formula of stay microorganisms, and the selling recommendations used to promote items containing micro organism. It comprises contributions from across the world recognized specialists in either technological know-how and undefined. Written with either expert and lay audiences in brain, Human future health: The Contribution of Microorganisms might be an critical textual content and reference resource for scientists, clinicians, and pharmaceutical/food technologists.

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1992b). Amino Acid Fermentation Substantial populations of amino acid fennenting bacteria are present in the large intestine. Many species, including the peptococci, acidaminococcus, veillonella, together with some fusobacteria, eubacteria and clostridia either do not, or only weakly fennent carbohydrates (Holdeman et al. 1977). These organisms and similar bacteria therefore fonn a metabolically and ecologically distinct group in the large bowel. The fennentation of amino acids by intestinal bacteria consists of a range of oxidation and reduction reactions.

10). Hydrogen generation by saccharolytic bacteria results mainly from the oxidation of pyruvate, formate or reduced pyridine nucleotides (NAD(P)H) and ferredoxins. Pyruvate probably has a central role in ~ metabolism in the large bowel, since it is energetically more favourable to produce ~ from this source than from other sources (Wolin 1976). Production of ~ from NADH is only thermodynamically possible at low p~ (Wolin 1974). In ecosystems such as the rumen, p~ is kept low through interspecies H2 transfer reactions between H2 producers and ~ utilising methanogenic bacteria (Wolin 1979).

1992a). 7 shows the results of a study on MB and SRB in two geographically diverse human populations. Breath CH4 concentrations, SRB activities and SRB carriage rates were detennined in 20 persons living in Cambridge (United Kingdom) and 20 in a rural South African village. It can be seen that the rural Africans were predominantly methanogenic, however a strong inverse relationship between methane production on one hand, and sulphate reduction on the other, was found in both populations. Six of the British subjects and 17 of the Africans were methanogenic.

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