Influence of Tumor Development on the Host by H. E. Kaiser (auth.), Lance A. Liotta (eds.)

By H. E. Kaiser (auth.), Lance A. Liotta (eds.)

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Response to insulin administration. : Temperature-dependent alterations in sugar transport in cells infected by temperature-sensitive mutant of the Rous sarcoma virus. : Glucose intolerance in sarcoma patients. Cancer 54(12):3022-3027, 1984 Papaioannou A: Tumors other than insulinomas associated with hypoglycemia. Surg Gynecol Obslet 123:1093-1109, 1966 Satomi N, Sakurai A, Haranaka K: Relationship of hypoglycemia to tumor necrosis factor production and antitumor activity: role of glucose, insulin, and macrophages.

TRUMP, IRENE K. BEREZESKY and KOOKMIN M. KIM INTRODUCTION cnOSOL The purpose of this paper is to critically review and analyze the literature concerning the role of cellular ion deregulation OTHER PROCESSES: Filament Contraction in growth and differentiation specifically as it relates to MicrotubuLe Dissolution tumor promotion. It has become evident in recent years that ion deregulation plays a significant role in cell division and cell death; concurrently, studies have been performed suggesting significant differences in neoplastic versus normal cells and in the effects of tumor promoters such as phorbol esters.

Serum copper levels have been suggested as a marker to confirm diagnosis and to follow malignant disease. The serum elevations, however, are most likely due to elevations in ceruloplasmin, the cop- 23 per-carrying protcin which is synthesized in the liver as an acute phase reactant (77). Iron is an essential mineral for cellular growth. Although severe iron deficiency is associated with an increased susceptibility to infection, borderline iron status may actually benefit the tumor-bearing host.

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