International Review of Cytology, Vol. 198 by Kwang W. Jeon

By Kwang W. Jeon

International overview of Cytology provides present advances and entire reports in mobilephone biology-both plant and animal. Articles handle constitution and regulate of gene expression, nucleocytoplasmic interactions, keep an eye on of cellphone improvement and differentiation, and telephone transformation and development. Authored via many of the premier scientists within the box, each one quantity offers up to date info and instructions for destiny examine. Key good points * Somite Formation and Patterning * Morphogenesis of the Egg Shell in Drosophila * phone Biology of Cytochrome P-450 within the Liver * replacement Protein Sorting Pathways * Structural Correlates of the Transepithelial Water shipping * Membrane Trafficking and Processing in Paramecium * position of typical Benzoxazinones within the Survival technique of crops

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1998). When caudal somites or PSM from older embryos that have had a longer exposure to the influence of the notochord in situ are cocultured with Wnt proteins alone, myogenic precursors differentiate. , 1998). There appears to be a difference in the requirement of continued Shh signaling in vivo and in 34 HIRSINGER ET AL. , 1998). The results of these experiments suggest that Shh and Wnt fulfill the criteria for the combinatorial signals from the notochord and the dorsal neural tube of the model proposed by Munsterberg and Lassar (1995).

The Lateral Plate Exerts a Lateralizing Signal on the Somite which Is Antagonized by Medial Structures 1. , 1997). When the somite is isolated from the lateral plate by a slit, lateral dermomyotomal markers such as Pax-3 and Sim-1 are lost; concommitantly, MyoD expression is up-regulated as if the lateral identity was converted to a medial identity. , 1995; 1996). , 1996). , 1997). These experiments demonstrated that the lateral plate produces a signal, which is required for the specification of lateral somitic identity.

The predominant 30 HIRSINGER ET AL. role of two genes, both encoding secreted molecules, has been extensively examined in vivo and in vitro. , 1998). Moreover, these factors have been shown to exhibit patterning activities in diverse systems (reviewed in Cadigan and Nusse, 1997; Tanabe and Jessell, 1996). Therefore, because these molecules are present at the right time and place, they appear to be good candidates for mediating somite patterning. 1. Shh Promotes Ventral Cell Fates whereas Wnt Proteins Specify Dorsal Lineages In vitro and in vivo experiments have provided evidence of a role for Shh in promoting sclerotome differentiation.

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