By Jerome Z. Litt
Relied upon through dermatologists and clinical practitioners the world over for its extraordinary sensible specialise in opposed results and cutaneous reactions, this article is the fundamental quick-reference instrument for sufferer care and drug safeguard. The response info for this new twentieth edition is compiled from the significant other site, that's up-to-date constantly, and contains prescription and over the counter medicines in addition to biologics, supplementations, and different scientific products—with tens of hundreds of thousands of inauspicious drug reactions, eruptions, and response styles. The textual content notes the variety of peer-reviewed references for response listings, the stated prevalence of a response, and clinically very important and most likely critical interactions among drugs.
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Extra resources for Litt's D.E.R.M. Drug Eruptions and Reactions Manual, 20th Edition
Contraindicated in patients with a history of hypersensitivity reactions to any of the penicillins. com isradipine, itraconazole, ixabepilone, ketoconazole, lidocaine, lopinavir, lorazepam, lovastatin, methadone, methylergonovine, methysergide, midazolam, mifepristone, nelfinavir, nevirapine, nicardipine, nifedipine, nimodipine, nisoldipine, nortriptyline, oral contraceptives, oxazepam, phenobarbital, phenytoin, pimozide, protriptyline, quazepam, quinidine, rapamycin, rifabutin, rifampin, ritonavir, saquinavir, sildenafil, simvastatin, St John’s wort, tacrolimus, temazepam, trazodone, triazolam, tricyclic antidepressants, trimipramine, verapamil, vitamin E, warfarin Pregnancy category: C Note: Safety and effectiveness in pediatric patients <4 years of age have not been established.
Aggrenox is aspirin and dipyridamole. 0] Proof [derm_#03] by Litt’s Drug Eruptions & Reactions Manual Petechiae  Pigmented purpuric eruption  Pityriasis rosea  Pruritus  Pseudolymphoma  Psoriasis  Purpura  Radiation recall dermatitis  Rash (1–10%) Stevens–Johnson syndrome  Toxic epidermal necrolysis (<1%)  Ulcerations (with dipyridamole) (<1%) Urticaria (1–10%)  Vasculitis  Hair Alopecia  Mucosal Aphthous stomatitis  Gingivitis (with dipyridamole) (<1%) Nasal polyps  Oral burn  Oral lichen planus  Oral mucosal eruption  Oral ulceration  Cardiovascular Flushing  Myocardial infarction  Central Nervous System Ageusia (with dipyridamole) (<1%) Anosmia  Dysgeusia Headache Paresthesias (with dipyridamole) (<1%) Neuromuscular/Skeletal Myalgia/Myositis/Myopathy/Myotoxicity (with dipyridamole) (1%) ATAZANAVIR ATAZANAVIR Trade name: Reyataz (Bristol-Myers Squibb) Indications: HIV infection Class: Antiretroviral, Protease inhibitor, HIV Half-life: 7 hours Clinically important, potentially hazardous interactions with: abiraterone, alfuzosin, amiodarone, antacids, aripiprazole, artemether / lumefantrine, atorvastatin, avanafil, bepridil, bosentan, buprenorphine, cabazitaxel, cabozantinib, cisapride, clarithromycin, colchicine, crizotinib, cyclosporine, darifenacin, dasatinib, dexlansoprazole, diltiazem, dofetilide, efavirenz, ergot derivatives, erlotinib, estrogens, etravirine, everolimus, famotidine, felodipine, fentanyl, fesoterodine, fluticasone, garlic, indinavir, irinotecan, itraconazole, ixabepilone, ketoconazole, lapatinib, lidocaine, lopinavir, lovastatin, maraviroc, marihuana, midazolam, mifepristone, nevirapine, nicardipine, nifedipine, omeprazole, oral contraceptives, paclitaxel, pantoprazole, pazopanib, pimozide, posaconazole, proton-pump inhibitors, quetiapine, quinidine, quinine, rabeprazole, raltegravir, ranolazine, rifabutin, rifampin, rilpivirine, ritonavir, rivaroxaban, romidepsin, rosuvastatin, salmeterol, saquinavir, sildenafil, simeprevir, simvastatin, sirolimus, solifenacin, St John’s wort, sunitinib, tacrolimus, tadalafil, telaprevir, telithromycin, temsirolimus, tenofovir, ticagrelor, tipranavir, trazodone, triazolam, tricyclic antidepressants, vardenafil, vemurafenib, verapamil, voriconazole, warfarin Pregnancy category: B Note: Use in pediatric patients <6 years of age is under investigation.
Skin Acneform eruption (>1%) Anaphylactoid reactions/Anaphylaxis Angioedema Candidiasis (>1%) Diaphoresis (>1%) Edema (>1%) Hematoma (>1%) Herpes simplex (>1%) Hot flashes (>1%) Pruritus (8%) Rash (>1%) Stevens–Johnson syndrome Urticaria (>1%) Trade name: Eliquis (Bristol-Myers Squibb) Indications: Reduce the risk of stroke and systemic embolism in patients with nonvalvular atrial fibrillation Class: Anticoagulant, Direct factor Xa inhibitor Half-life: 5–12 hours Clinically important, potentially hazardous interactions with: carbamazepine, darunavir, phenytoin, rifampin, St John’s wort, tipranavir, voriconazole Pregnancy category: B Note: Contraindicated in patients with active pathological bleeding.