By Eugenio E. Muller
Neurotransmitters And Anterior Pituitary Function
summary: Neurotransmitters And Anterior Pituitary functionality
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Extra resources for Neurotransmitters and Anterior Pituitary Function
Dorsomedialis hypothalami pars medialis (tuberoin fundibular DA system). , 1972; Bjorklund et al, 1973a) (Fig. 9). Although it was initially postulated that N E terminals Fig. 9 Transverse section through the hypothalamus-ME region. A dense accumulation of fluorescent nerves is observed in close proximity to the capillary plexus in the external layer. Fewer more discrete varicose fibers are observed in the internal layer of the M E . Low fluorescence ARC nucleus cell bodies are present (arrows).
Throughout the gland, N E concentrations are low, about one-tenth that of DA. Epinephrine was not detected in significant concentrations in the pituitary gland (Bjorklund and Falck, 1969; Bjorklund et al, 1970; Iwata and Ishii, 1969), a finding consistent with the reported lack of PNMT activity (Saavedra et al, 1975). Table VI reports the distribution of some biogenic amines in the rat pituitary gland. In the anterior lobe of the pituitary strong green to yellow-green C A fluorescence is present in several PAS-positive cells o f cats, dogs, pigs, but not rats (Dahlstrom and Fuxe, 1966; Fuxe and Hokfelt, 1969).
1967) A y u k a w a et al. (1968) Taylor et al. (1968) P o r t e r s al. (1962) U d e n f r i e n d et al. (1965); S p e c t o r et al. (1965) H a n s o n (1965); C o r r o d i a n d H a n s o n (1966) U d e n f r i e n d et al. (1965); G o l d s t e i n a n d Weiss (1965); S p e c t o r et al. (1965) M c G e e r et al. , 1972). , 1967) C o p p e r chelating agent Inhibition at peripheral a n d c e n t r a l sites H y p o t e n s i v e effect; stimulation of medullary α-receptors through formation of α - Μ Ν Ε ( L a v e r t y , 1973) G o l d s t e i n et al.